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Monday, September 29, 2025

Liver fat, not weight, predicts health risks in children with obesity, scientists say

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Israeli scientists have uncovered a key insight into childhood obesity: it’s the fat buildup in the liver, not just a child’s weight, that signals real health risks. Researchers from Tel Aviv University and Dana-Dwek Children’s Hospital shared these findings, highlighting how some obese kids stay healthy while others face serious issues like type 2 diabetes, high blood pressure, heart disease, and even liver damage down the line.

In their study, the team looked at 31 children with obesity in Israel. They wanted to figure out why some develop metabolic problems and others don’t. The big takeaway? Kids already showing health issues had livers with about 14% fat—more than double the 6% found in obese children who were otherwise healthy.

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“This is a snapshot study—we examined the kids at one moment in time, not over years,” explained Ron Sternfeld, a doctoral student on the team. “We can’t prove cause and effect, but the difference is clear: some obese children keep their metabolic health intact.”

To get precise measurements, the researchers used magnetic resonance spectroscopy (MRS) during MRI scans. This non-invasive technique directly checks liver fat levels, something rare in kids’ studies. They also ran full medical exams and dug into the children’s health records from before birth.

Surprisingly, other risks like fat around the organs (visceral fat) showed no big differences between the healthy and unhealthy groups. “We tested tons of factors, and liver fat stood out as the main divider,” Sternfeld said. Anything over 5.5% liver fat ties to risks like diabetes, sleep apnea, and hypertension. Yet, some obese kids avoid fatty liver altogether.

Lead researcher Prof. Yftach Gepner points to diet as the game-changer. The unhealthy kids ate more sodium, processed foods, and saturated fats from red meat and other animal proteins. Switching to better eating habits, like a Mediterranean diet rich in fruits, veggies, whole grains, and healthy fats, could shield the liver and prevent problems—even without weight loss.

Prenatal history matters too. Kids in the unhealthy group were three times more likely to come from high-risk pregnancies, showing how early life sets the stage for later metabolic health.

“Obese children can absolutely be healthy,” Gepner noted. “If cutting calories is tough, focus on nutrition quality to cut liver fat. The liver drives metabolism, so tracking it should be a priority in preventive care for childhood obesity.”

The study offers real tips for parents and doctors: Cut back on processed foods, salt, and saturated fats to tame liver fat. Start early screenings with safe imaging tools to spot at-risk kids. Then, provide nutrition advice and exercise plans to fend off obesity-related diseases like diabetes and high blood pressure. This approach could transform how we handle fatty liver disease in children and boost long-term health.


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